Göran Engberg Selected Research

Kynurenic Acid (Kynurenate)

11/2021	GRK3 deficiency elicits brain immune activation and psychosis.
1/2021	Blockade of KAT II Facilitates LTP in Kynurenine 3-Monooxygenase Depleted Mice.
1/2019	Lipopolysaccharide Increases Cortical Kynurenic Acid and Deficits in Reference Memory in Mice.
1/2019	Peripheral and central levels of kynurenic acid in bipolar disorder subjects and healthy controls.
1/2017	Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria.
1/2017	Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.
1/2017	The kynurenine pathway in schizophrenia and bipolar disorder.
3/2016	Inhibition of kynurenine aminotransferase II reduces activity of midbrain dopamine neurons.
1/2015	Chronic Antipsychotic Treatment in the Rat - Effects on Brain Interleukin-8 and Kynurenic Acid.
2/2014	Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid.

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Göran Engberg Research Topics

Disease

26	Schizophrenia (Dementia Praecox) 08/2022 - 01/2003
9	Bipolar Disorder (Manic Depressive Psychosis) 11/2021 - 05/2010
8	Psychotic Disorders (Schizoaffective Disorder) 08/2022 - 03/2016
4	Cognitive Dysfunction 01/2021 - 01/2017
3	Mental Disorders (Mental Disorder) 01/2019 - 01/2009
3	Central Nervous System Infections (Central Nervous System Infection) 01/2017 - 12/2008
2	Infections 02/2014 - 12/2008
2	Virus Diseases (Viral Diseases) 02/2014 - 01/2013
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Neuroinflammatory Diseases 01/2019
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2019
1	Inflammation (Inflammations) 01/2019
1	Cerebral Malaria 01/2017
1	Communicable Diseases (Infectious Diseases) 01/2017
1	Coma (Comas) 01/2017
1	Human Influenza (Influenza) 02/2014
1	Encephalitis (Encephalitis, Rasmussen) 01/2013
1	Mania (Manias) 03/2011
1	Treatment-Resistant Schizophrenia 08/2008

Drug/Important Bio-Agent (IBA)

21	Kynurenic Acid (Kynurenate)IBA 11/2021 - 01/2003
10	KynurenineIBA 01/2021 - 12/2008
7	CytokinesIBA 01/2019 - 03/2011
7	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2017 - 05/2004
6	Antipsychotic Agents (Antipsychotics)IBA 01/2019 - 05/2004
5	Tryptophan (L-Tryptophan)FDA Link 01/2019 - 05/2010
4	Dopamine (Intropin)FDA LinkGeneric 08/2022 - 01/2003
4	Kynurenine 3-Monooxygenase (Kynurenine 3 Monooxygenase)IBA 01/2018 - 04/2011
3	Polytetrafluoroethylene (Teflon)FDA Link 01/2022 - 01/2019
3	Proteins (Proteins, Gene)FDA Link 11/2021 - 03/2011
3	InterleukinsIBA 01/2017 - 03/2015
2	Pharmaceutical PreparationsIBA 01/2019 - 06/2005
2	Quinolinic AcidIBA 01/2017 - 01/2014
2	Interleukin-6 (Interleukin 6)IBA 01/2017 - 03/2015
2	Olanzapine (Zyprexa)FDA Link 03/2015 - 05/2012
2	Clozapine (Clozaril)FDA LinkGeneric 08/2008 - 05/2004
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 06/2005 - 05/2004
2	Glutamic Acid (Glutamate)FDA Link 01/2005 - 01/2003
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 08/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 11/2021
1	G-Protein-Coupled Receptor KinasesIBA 11/2021
1	Immunomodulating AgentsIBA 11/2021
1	Synaptosomal-Associated Protein 25IBA 06/2020
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	BenzodiazepinesIBA 01/2019
1	LipopolysaccharidesIBA 01/2019
1	N-Methylaspartate (NMDA)IBA 01/2019
1	ChemokinesIBA 01/2019
1	Interleukin-18 (Interleukin 18)IBA 01/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017
1	EnzymesIBA 01/2017
1	Interleukin-8 (Interleukin 8)IBA 01/2017
1	Glutamate Receptors (Glutamate Receptor)IBA 01/2017
1	kynurenine-oxoglutarate transaminaseIBA 01/2017
1	N 30IBA 03/2011
1	Amphetamine (Amfetamine)FDA LinkGeneric 05/2009
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 12/2007
1	Serine (L-Serine)FDA Link 06/2005
1	Glutamine (L-Glutamine)FDA Link 01/2005

Therapy/Procedure

1	Therapeutics 10/2015